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Kenji Honda Selected Research

(4- (m- Chlorophenylcarbamoyloxy)- 2- butynyl)trimethylammonium Chloride

2/2020Muscarinic M1 receptors stimulated by intracerebroventricular administration of McN-A-343 reduces the nerve injury-induced mechanical hypersensitivity via GABAB receptors rather than GABAA receptors in mice.
1/2019Stimulating muscarinic M1 receptors in the anterior cingulate cortex reduces mechanical hypersensitivity via GABAergic transmission in nerve injury rats.
11/2004Intrathecal clonidine inhibits mechanical allodynia via activation of the spinal muscarinic M1 receptor in streptozotocin-induced diabetic mice.

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Kenji Honda Research Topics

Disease

5Hypersensitivity (Allergy)
02/2020 - 11/2004
3Hyperalgesia
03/2009 - 11/2004
1Chronic Pain
01/2019
1Diabetic Neuropathies (Diabetic Neuropathy)
03/2009
1Pain (Aches)
03/2009
1Neuralgia (Stump Neuralgia)
10/2002
1Tachycardia (Tachyarrhythmias)
05/2002
1Hypotension (Low Blood Pressure)
05/2002

Drug/Important Bio-Agent (IBA)

4Muscarinic M1 ReceptorIBA
02/2020 - 11/2004
3(4- (m- Chlorophenylcarbamoyloxy)- 2- butynyl)trimethylammonium ChlorideIBA
02/2020 - 11/2004
3Streptozocin (Streptozotocin)FDA Link
03/2009 - 11/2004
1BicucullineIBA
02/2020
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
02/2020
1Dizocilpine Maleate (Dizocilpine)IBA
02/2020
1GABA Receptors (GABA Receptor)IBA
02/2020
1Aminobutyrates (Aminobutyric Acid)IBA
01/2019
1Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
01/2019
1Cholinergic Agents (Cholinergics)IBA
01/2019
1BaclofenFDA LinkGeneric
06/2018
1pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acidIBA
03/2009
1Opioid Analgesics (Opioids)IBA
03/2009
1Analgesics (Analgesic Drugs)IBA
03/2009
12',3'-O-(2,4,6-trinitrophenyl)adenosine 5'-triphosphateIBA
03/2009
1Protein Kinase CIBA
05/2007
1calphostin CIBA
05/2007
11- (5- Isoquinolinesulfonyl)- 2- Methylpiperazine (H 7)IBA
05/2007
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
05/2007
1Clonidine (ST 155)FDA LinkGeneric
11/2004
1Messenger RNA (mRNA)IBA
10/2002
1ONO AE 248IBA
05/2002
19- deoxy- 9- chloro- 15- deoxy- 16- hydroxy- 17,17- trimethylene- 19,20- didehydroprostaglandin E2IBA
05/2002
1ONO-AE1-329IBA
05/2002

Therapy/Procedure

3Ligation
02/2020 - 06/2018
1Spinal Injections
05/2007